Quantitative assessment of the degradation of aggregated TDP-43 mediated by the ubiquitin proteasome system and macroautophagy.

Cascella, Roberta

Quantitative assessment of the degradation of aggregated TDP-43 mediated by the ubiquitin proteasome system and macroautophagy. [electronic resource] - FASEB journal : official publication of the Federation of American Societies for Experimental Biology 12 2017 - 5609-5624 p. digital

Publication Type: Journal Article

1530-6860

10.1096/fj.201700292RR doi


Animals
Autophagy--genetics
Cell Line
DNA-Binding Proteins--genetics
Humans
Inclusion Bodies--metabolism
Mice
Motor Neuron Disease--genetics
Proteasome Endopeptidase Complex--metabolism
Protein Aggregation, Pathological--genetics
Proteolysis
RNA Interference
Ubiquitin--genetics