Linking High-Throughput Screens to Identify MoAs and Novel Inhibitors of Mycobacterium tuberculosis Dihydrofolate Reductase.

Santa Maria, John P

Linking High-Throughput Screens to Identify MoAs and Novel Inhibitors of Mycobacterium tuberculosis Dihydrofolate Reductase. [electronic resource] - ACS chemical biology 09 2017 - 2448-2456 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Intramural

1554-8937

10.1021/acschembio.7b00468 doi


Antitubercular Agents--chemistry
Drug Evaluation, Preclinical
Folic Acid Antagonists--chemistry
HeLa Cells
High-Throughput Screening Assays
Humans
Ligands
Molecular Docking Simulation
Mycobacterium tuberculosis--drug effects
Tetrahydrofolate Dehydrogenase--metabolism
Tuberculosis--drug therapy