Pyridine-pyrimidine amides that prevent HGF-induced epithelial scattering by two distinct mechanisms.
Siddiqui-Jain, Adam
Pyridine-pyrimidine amides that prevent HGF-induced epithelial scattering by two distinct mechanisms. [electronic resource] - Bioorganic & medicinal chemistry letters 09 2017 - 3992-4000 p. digital
Publication Type: Journal Article
1464-3405
10.1016/j.bmcl.2017.07.063 doi
Amides--chemical synthesis
Antineoplastic Agents--chemical synthesis
Cell Line, Tumor
Cell Movement--drug effects
Cell Proliferation--drug effects
Dose-Response Relationship, Drug
Drug Screening Assays, Antitumor
Epithelial Cells--drug effects
Hepatocyte Growth Factor--antagonists & inhibitors
Humans
MCF-7 Cells
Molecular Structure
Pyridines--chemical synthesis
Pyrimidines--chemical synthesis
Structure-Activity Relationship
Pyridine-pyrimidine amides that prevent HGF-induced epithelial scattering by two distinct mechanisms. [electronic resource] - Bioorganic & medicinal chemistry letters 09 2017 - 3992-4000 p. digital
Publication Type: Journal Article
1464-3405
10.1016/j.bmcl.2017.07.063 doi
Amides--chemical synthesis
Antineoplastic Agents--chemical synthesis
Cell Line, Tumor
Cell Movement--drug effects
Cell Proliferation--drug effects
Dose-Response Relationship, Drug
Drug Screening Assays, Antitumor
Epithelial Cells--drug effects
Hepatocyte Growth Factor--antagonists & inhibitors
Humans
MCF-7 Cells
Molecular Structure
Pyridines--chemical synthesis
Pyrimidines--chemical synthesis
Structure-Activity Relationship