A genetic variant in the catechol-O-methyl transferase (COMT) gene is related to age-dependent differences in the therapeutic effect of calcium-channel blockers.
Xu, Jiayue
A genetic variant in the catechol-O-methyl transferase (COMT) gene is related to age-dependent differences in the therapeutic effect of calcium-channel blockers. [electronic resource] - Medicine Jul 2017 - e7029 p. digital
Publication Type: Journal Article
1536-5964
10.1097/MD.0000000000007029 doi
Age Factors
Aged
Aged, 80 and over
Aging--drug effects
Antihypertensive Agents--therapeutic use
Aromatase--genetics
Blood Pressure--drug effects
Calcium Channel Blockers--therapeutic use
Catechol O-Methyltransferase--genetics
Cohort Studies
Female
Genotyping Techniques
Glucuronosyltransferase--genetics
Humans
Male
Middle Aged
Pharmacogenomic Variants
Switzerland
A genetic variant in the catechol-O-methyl transferase (COMT) gene is related to age-dependent differences in the therapeutic effect of calcium-channel blockers. [electronic resource] - Medicine Jul 2017 - e7029 p. digital
Publication Type: Journal Article
1536-5964
10.1097/MD.0000000000007029 doi
Age Factors
Aged
Aged, 80 and over
Aging--drug effects
Antihypertensive Agents--therapeutic use
Aromatase--genetics
Blood Pressure--drug effects
Calcium Channel Blockers--therapeutic use
Catechol O-Methyltransferase--genetics
Cohort Studies
Female
Genotyping Techniques
Glucuronosyltransferase--genetics
Humans
Male
Middle Aged
Pharmacogenomic Variants
Switzerland