Granulocyte colony-stimulating factor (GCSF) fused with Fc Domain produced from E. coli is less effective than Polyethylene Glycol-conjugated GCSF.
Do, Bich Hang
Granulocyte colony-stimulating factor (GCSF) fused with Fc Domain produced from E. coli is less effective than Polyethylene Glycol-conjugated GCSF. [electronic resource] - Scientific reports 07 2017 - 6480 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
2045-2322
10.1038/s41598-017-06726-7 doi
Animals
Cell Line
Cell Proliferation--drug effects
Escherichia coli--genetics
Granulocyte Colony-Stimulating Factor--genetics
Humans
Hydrogen-Ion Concentration
Immunoglobulin Fc Fragments--genetics
Neutropenia--drug therapy
Polyethylene Glycols--chemistry
Protein Engineering--methods
Rats, Sprague-Dawley
Recombinant Proteins--genetics
Granulocyte colony-stimulating factor (GCSF) fused with Fc Domain produced from E. coli is less effective than Polyethylene Glycol-conjugated GCSF. [electronic resource] - Scientific reports 07 2017 - 6480 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
2045-2322
10.1038/s41598-017-06726-7 doi
Animals
Cell Line
Cell Proliferation--drug effects
Escherichia coli--genetics
Granulocyte Colony-Stimulating Factor--genetics
Humans
Hydrogen-Ion Concentration
Immunoglobulin Fc Fragments--genetics
Neutropenia--drug therapy
Polyethylene Glycols--chemistry
Protein Engineering--methods
Rats, Sprague-Dawley
Recombinant Proteins--genetics