Autophagy-ERK1/2-Involved Disinhibition of Hippocampal Neurons Contributes to the Pre-Synaptic Toxicity Induced by Aβ42 Exposure.

Yin, Yanling

Autophagy-ERK1/2-Involved Disinhibition of Hippocampal Neurons Contributes to the Pre-Synaptic Toxicity Induced by Aβ42 Exposure. [electronic resource] - Journal of Alzheimer's disease : JAD 2017 - 851-869 p. digital

Publication Type: Journal Article

1875-8908

10.3233/JAD-170246 doi


Amyloid beta-Peptides--toxicity
Animals
Autophagy--drug effects
Cells, Cultured
Curcumin--pharmacology
Disks Large Homolog 4 Protein--metabolism
Embryo, Mammalian
Enzyme Inhibitors--pharmacology
Female
Glutamate Decarboxylase--metabolism
Hippocampus--cytology
L-Lactate Dehydrogenase--metabolism
MAP Kinase Signaling System--drug effects
Membrane Potentials--drug effects
Microscopy, Electron, Transmission
Models, Biological
Neural Inhibition--drug effects
Neurons--cytology
Patch-Clamp Techniques
Peptide Fragments--toxicity
Pregnancy
Presynaptic Terminals--drug effects
Rats
Synaptic Potentials--drug effects
Synaptophysin--metabolism
gamma-Aminobutyric Acid--metabolism