Development of a Potent Inhibitor of the Plasmodium Proteasome with Reduced Mammalian Toxicity.
LaMonte, Gregory M
Development of a Potent Inhibitor of the Plasmodium Proteasome with Reduced Mammalian Toxicity. [electronic resource] - Journal of medicinal chemistry 08 2017 - 6721-6732 p. digital
Publication Type: Journal Article
1520-4804
10.1021/acs.jmedchem.7b00671 doi
Antimalarials--chemical synthesis
Artemisinins--pharmacology
Dipeptides--chemical synthesis
Drug Design
Enzyme Assays
Hep G2 Cells
Humans
Molecular Docking Simulation
Oligopeptides--chemical synthesis
Plasmodium falciparum--drug effects
Proteasome Endopeptidase Complex--metabolism
Proteasome Inhibitors--chemical synthesis
Saccharomyces cerevisiae--drug effects
Development of a Potent Inhibitor of the Plasmodium Proteasome with Reduced Mammalian Toxicity. [electronic resource] - Journal of medicinal chemistry 08 2017 - 6721-6732 p. digital
Publication Type: Journal Article
1520-4804
10.1021/acs.jmedchem.7b00671 doi
Antimalarials--chemical synthesis
Artemisinins--pharmacology
Dipeptides--chemical synthesis
Drug Design
Enzyme Assays
Hep G2 Cells
Humans
Molecular Docking Simulation
Oligopeptides--chemical synthesis
Plasmodium falciparum--drug effects
Proteasome Endopeptidase Complex--metabolism
Proteasome Inhibitors--chemical synthesis
Saccharomyces cerevisiae--drug effects