Deletion of eIF2β lysine stretches creates a dominant negative that affects the translation and proliferation in human cell line: A tool for arresting the cell growth.

Salton, Gabrielle Dias

Deletion of eIF2β lysine stretches creates a dominant negative that affects the translation and proliferation in human cell line: A tool for arresting the cell growth. [electronic resource] - Cancer biology & therapy Aug 2017 - 560-570 p. digital

Publication Type: Journal Article

1555-8576

10.1080/15384047.2017.1345383 doi


Apoptosis--genetics
Binding Sites
Cell Nucleus--metabolism
Cell Proliferation--genetics
Cell Survival--genetics
Cytoplasm--metabolism
Eukaryotic Initiation Factor-2B--genetics
G2 Phase Cell Cycle Checkpoints--genetics
HEK293 Cells
Humans
Molecular Targeted Therapy--methods
Mutagenesis, Site-Directed
Neoplasms--therapy
Polylysine--genetics
Protein Binding
Protein Biosynthesis--genetics
Protein Transport
RNA, Messenger--metabolism
Sequence Deletion--genetics