Inhibition of CDK-mediated Smad3 phosphorylation reduces the Pin1-Smad3 interaction and aggressiveness of triple negative breast cancer cells.

Thomas, Alexandra L

Inhibition of CDK-mediated Smad3 phosphorylation reduces the Pin1-Smad3 interaction and aggressiveness of triple negative breast cancer cells. [electronic resource] - Cell cycle (Georgetown, Tex.) Aug 2017 - 1453-1464 p. digital

Publication Type: Journal Article

1551-4005

10.1080/15384101.2017.1338988 doi


Adenosine--analogs & derivatives
Cell Line, Tumor
Cell Movement--drug effects
Cyclin-Dependent Kinase 2--antagonists & inhibitors
Cyclin-Dependent Kinase 4--antagonists & inhibitors
Female
Humans
NIMA-Interacting Peptidylprolyl Isomerase--genetics
Phosphorylation--drug effects
Protein Binding
Signal Transduction--drug effects
Smad3 Protein--genetics
Transforming Growth Factor beta--genetics
Triple Negative Breast Neoplasms--metabolism