From in vitro to in vivo: Integration of the virtual cell based assay with physiologically based kinetic modelling.

Paini, Alicia

From in vitro to in vivo: Integration of the virtual cell based assay with physiologically based kinetic modelling. [electronic resource] - Toxicology in vitro : an international journal published in association with BIBRA Dec 2017 - 241-248 p. digital

Publication Type: Journal Article

1879-3177

10.1016/j.tiv.2017.06.015 doi


Allylbenzene Derivatives
Anisoles--pharmacokinetics
Cell Line
Cell Survival--drug effects
Chemical and Drug Induced Liver Injury--metabolism
DNA Adducts--metabolism
Flavoring Agents--pharmacokinetics
Humans
Liver--metabolism
Membrane Potential, Mitochondrial--drug effects
Models, Biological
Risk Assessment