CRISPR/Cas9 targeting of GPRC6A suppresses prostate cancer tumorigenesis in a human xenograft model.

Ye, Ruisong

CRISPR/Cas9 targeting of GPRC6A suppresses prostate cancer tumorigenesis in a human xenograft model. [electronic resource] - Journal of experimental & clinical cancer research : CR 06 2017 - 90 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1756-9966

10.1186/s13046-017-0561-x doi


Animals
CRISPR-Cas Systems
Cell Line, Tumor
Cell Movement--genetics
Cell Proliferation
Cell Transformation, Neoplastic--genetics
Disease Models, Animal
Gene Editing
Gene Order
Gene Targeting
Genetic Vectors--genetics
HEK293 Cells
Humans
Ligands
Male
Mice
Prostatic Neoplasms--genetics
Receptors, G-Protein-Coupled--chemistry
Xenograft Model Antitumor Assays