Bile Salt Homeostasis in Normal and Bsep Gene Knockout Rats with Single and Repeated Doses of Troglitazone.

Cheng, Yaofeng

Bile Salt Homeostasis in Normal and Bsep Gene Knockout Rats with Single and Repeated Doses of Troglitazone. [electronic resource] - The Journal of pharmacology and experimental therapeutics 09 2017 - 385-394 p. digital

Publication Type: Journal Article

1521-0103

10.1124/jpet.117.242370 doi


ATP Binding Cassette Transporter, Subfamily B, Member 11
ATP-Binding Cassette Transporters--genetics
Animals
Bile--metabolism
Bile Acids and Salts--metabolism
Cholesterol 7-alpha-Hydroxylase--biosynthesis
Chromans--pharmacology
Gene Knockout Techniques
Homeostasis--drug effects
Hypoglycemic Agents--pharmacology
Liver--drug effects
Male
RNA, Messenger--biosynthesis
Rats
Rats, Sprague-Dawley
Thiazolidinediones--pharmacology
Troglitazone
Up-Regulation--drug effects