Ruthenium Complexes are pH-Activated Metallo Prodrugs (pHAMPs) with Light-Triggered Selective Toxicity Toward Cancer Cells.

Qu, Fengrui

Ruthenium Complexes are pH-Activated Metallo Prodrugs (pHAMPs) with Light-Triggered Selective Toxicity Toward Cancer Cells. [electronic resource] - Inorganic chemistry Jul 2017 - 7519-7532 p. digital

Publication Type: Journal Article

1520-510X

10.1021/acs.inorgchem.7b01065 doi


Antineoplastic Agents--chemical synthesis
Cell Proliferation--drug effects
Coordination Complexes--chemical synthesis
Crystallography, X-Ray
Dose-Response Relationship, Drug
Drug Screening Assays, Antitumor
Humans
Hydrogen-Ion Concentration
Light
Models, Molecular
Molecular Structure
Prodrugs--chemical synthesis
Quantum Theory
Ruthenium--chemistry
Structure-Activity Relationship
Tumor Cells, Cultured