Downregulation of Notch1 inhibits the invasion and metastasis of human gastric cancer cells SGC7901 and MKN74 in vitro through PTEN activation and dephosphorylation of Akt and FAK.

Zhang, Xue-Song

Downregulation of Notch1 inhibits the invasion and metastasis of human gastric cancer cells SGC7901 and MKN74 in vitro through PTEN activation and dephosphorylation of Akt and FAK. [electronic resource] - Molecular medicine reports Aug 2017 - 2318-2324 p. digital

Publication Type: Journal Article

1791-3004

10.3892/mmr.2017.6791 doi


Cell Line, Tumor
Cell Movement
Down-Regulation
Focal Adhesion Kinase 1--genetics
Humans
PTEN Phosphohydrolase--genetics
Phosphorylation
Proto-Oncogene Proteins c-akt--genetics
RNA Interference
RNA, Messenger--metabolism
RNA, Small Interfering--metabolism
Receptor, Notch1--antagonists & inhibitors
Stomach Neoplasms--metabolism