Targeting glioma stem cells in vivo by a G-quadruplex-stabilizing synthetic macrocyclic hexaoxazole.

Nakamura, Takahiro

Targeting glioma stem cells in vivo by a G-quadruplex-stabilizing synthetic macrocyclic hexaoxazole. [electronic resource] - Scientific reports 06 2017 - 3605 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

2045-2322

10.1038/s41598-017-03785-8 doi


Animals
Antineoplastic Agents--administration & dosage
Apoptosis--drug effects
Cell Cycle Checkpoints--drug effects
Cell Proliferation--drug effects
Cell Survival--drug effects
G-Quadruplexes--drug effects
Glioma--drug therapy
Heterografts
Humans
Macrocyclic Compounds--administration & dosage
Mice
Neoplasm Transplantation
Neoplastic Stem Cells--drug effects
Oxazoles--administration & dosage
Treatment Outcome
Tumor Cells, Cultured