Nanoparticle-mediated knockdown of DNA repair sensitizes cells to radiotherapy and extends survival in a genetic mouse model of glioblastoma.

Kievit, Forrest M

Nanoparticle-mediated knockdown of DNA repair sensitizes cells to radiotherapy and extends survival in a genetic mouse model of glioblastoma. [electronic resource] - Nanomedicine : nanotechnology, biology, and medicine Oct 2017 - 2131-2139 p. digital

Publication Type: Journal Article

1549-9642

10.1016/j.nano.2017.06.004 doi


Animals
Brain--metabolism
Brain Neoplasms--genetics
Cell Line, Tumor
DNA Repair
DNA-(Apurinic or Apyrimidinic Site) Lyase--genetics
Disease Models, Animal
Drug Carriers--chemistry
Glioblastoma--genetics
Mice
Nanoparticles--chemistry
RNA, Small Interfering--administration & dosage
RNAi Therapeutics--methods