Sequential combination of docetaxel with a SHP-1 agonist enhanced suppression of p-STAT3 signaling and apoptosis in triple negative breast cancer cells.

Liu, Chun-Yu

Sequential combination of docetaxel with a SHP-1 agonist enhanced suppression of p-STAT3 signaling and apoptosis in triple negative breast cancer cells. [electronic resource] - Journal of molecular medicine (Berlin, Germany) Sep 2017 - 965-975 p. digital

Publication Type: Journal Article

1432-1440

10.1007/s00109-017-1549-x doi


Animals
Antineoplastic Agents--pharmacology
Apoptosis--drug effects
Cell Line, Tumor
Cell Proliferation--drug effects
Disease Models, Animal
Docetaxel
Drug Synergism
Female
Gene Expression Regulation, Neoplastic
Humans
Mice
Phenyl Ethers--pharmacology
Phenylurea Compounds--pharmacology
Prognosis
Protein Tyrosine Phosphatase, Non-Receptor Type 6--genetics
STAT3 Transcription Factor--metabolism
Signal Transduction--drug effects
Taxoids--pharmacology
Transcription, Genetic
Triple Negative Breast Neoplasms--genetics
Xenograft Model Antitumor Assays