A novel, somatic, transforming mutation in the extracellular domain of Epidermal Growth Factor Receptor identified in myeloproliferative neoplasm.

Casolari, D A

A novel, somatic, transforming mutation in the extracellular domain of Epidermal Growth Factor Receptor identified in myeloproliferative neoplasm. [electronic resource] - Scientific reports 05 2017 - 2467 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

2045-2322

10.1038/s41598-017-02655-7 doi


Amino Acid Sequence
Cell Differentiation--drug effects
Cell Line, Tumor
Clone Cells
ErbB Receptors--genetics
Erythroblasts--drug effects
Erythropoietin--pharmacology
Gene Expression
Humans
Janus Kinase 2--genetics
Leukemia, Erythroblastic, Acute--genetics
Mutation
Polycythemia Vera--genetics
Primary Myelofibrosis--genetics
Protein Multimerization
Sequence Alignment
Sequence Homology, Amino Acid
Signal Transduction