Metformin alters the gut microbiome of individuals with treatment-naive type 2 diabetes, contributing to the therapeutic effects of the drug.

Wu, Hao

Metformin alters the gut microbiome of individuals with treatment-naive type 2 diabetes, contributing to the therapeutic effects of the drug. [electronic resource] - Nature medicine Jul 2017 - 850-858 p. digital

Publication Type: Journal Article; Randomized Controlled Trial

1546-170X

10.1038/nm.4345 doi


Animals
Bile Acids and Salts--metabolism
DNA, Bacterial--analysis
Diabetes Mellitus, Type 2--drug therapy
Double-Blind Method
Fatty Acids, Volatile--metabolism
Fecal Microbiota Transplantation
Feces--chemistry
Female
Gastrointestinal Microbiome--genetics
Germ-Free Life
Glucose Tolerance Test
Humans
Hypoglycemic Agents--therapeutic use
In Vitro Techniques
Male
Metagenomics
Metformin--therapeutic use
Mice
Middle Aged