2-Hydroxypropyl-beta-cyclodextrin (HPβCD) reduces age-related lipofuscin accumulation through a cholesterol-associated pathway.

Gaspar, Jason

2-Hydroxypropyl-beta-cyclodextrin (HPβCD) reduces age-related lipofuscin accumulation through a cholesterol-associated pathway. [electronic resource] - Scientific reports 05 2017 - 2197 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

2045-2322

10.1038/s41598-017-02387-8 doi


2-Hydroxypropyl-beta-cyclodextrin--pharmacology
Age Factors
Apoptosis
Cell Line
Cell Membrane Permeability
Cholesterol--metabolism
Fibroblasts--metabolism
Humans
Lipofuscin--metabolism
Lysosomes--metabolism
Metabolic Networks and Pathways