Basic fibroblast growth factor reduces scar by inhibiting the differentiation of epidermal stem cells to myofibroblasts via the Notch1/Jagged1 pathway.

Wang, Peng

Basic fibroblast growth factor reduces scar by inhibiting the differentiation of epidermal stem cells to myofibroblasts via the Notch1/Jagged1 pathway. [electronic resource] - Stem cell research & therapy 05 2017 - 114 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1757-6512

10.1186/s13287-017-0549-7 doi


Animals
Animals, Newborn
Cell Differentiation--drug effects
Cell Proliferation--drug effects
Cicatrix--pathology
Collagen Type I--metabolism
Dipeptides--pharmacology
Embryonic Stem Cells--cytology
Epidermis--pathology
Female
Fibroblast Growth Factor 2--pharmacology
Jagged-1 Protein--metabolism
Myofibroblasts--drug effects
Rabbits
Rats, Sprague-Dawley
Re-Epithelialization--drug effects
Receptors, Notch--metabolism
Regeneration--drug effects
Signal Transduction--drug effects
Stem Cells--drug effects
Transforming Growth Factor beta1--pharmacology