Myocyte enhancer factor 2D promotes colorectal cancer angiogenesis downstream of hypoxia-inducible factor 1α.

Xiang, Junyu

Myocyte enhancer factor 2D promotes colorectal cancer angiogenesis downstream of hypoxia-inducible factor 1α. [electronic resource] - Cancer letters 08 2017 - 117-126 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1872-7980

10.1016/j.canlet.2017.04.037 doi


Animals
Binding Sites
Biomarkers, Tumor--genetics
Caco-2 Cells
Colorectal Neoplasms--blood supply
Culture Media, Conditioned--metabolism
Cytokines--metabolism
Female
Gene Expression Regulation, Neoplastic
HCT116 Cells
HT29 Cells
Human Umbilical Vein Endothelial Cells--metabolism
Humans
Hypoxia-Inducible Factor 1, alpha Subunit--genetics
MEF2 Transcription Factors--genetics
Male
Mice, Inbred BALB C
Mice, Nude
Microvessels--metabolism
Middle Aged
Neovascularization, Pathologic
Paracrine Communication
Platelet Endothelial Cell Adhesion Molecule-1--metabolism
Prognosis
Promoter Regions, Genetic
RNA Interference
Signal Transduction
Time Factors
Transcriptional Activation
Transfection
Tumor Burden
Tumor Hypoxia
Tumor Microenvironment