Identification of 4-arylidene curcumin analogues as novel proteasome inhibitors for potential anticancer agents targeting 19S regulatory particle associated deubiquitinase.

Yue, Xin

Identification of 4-arylidene curcumin analogues as novel proteasome inhibitors for potential anticancer agents targeting 19S regulatory particle associated deubiquitinase. [electronic resource] - Biochemical pharmacology 08 2017 - 29-50 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1873-2968

10.1016/j.bcp.2017.04.032 doi


A549 Cells
Animals
Antineoplastic Agents--chemistry
CHO Cells
Cell Proliferation--drug effects
Cricetinae
Cricetulus
Curcumin--analogs & derivatives
Deubiquitinating Enzymes--antagonists & inhibitors
Dose-Response Relationship, Drug
Drug Delivery Systems--methods
Humans
Proteasome Endopeptidase Complex--metabolism
Proteasome Inhibitors--chemistry