Astemizole protects against human umbilical vein endothelial cell injury induced by hydrogen peroxide via the p53 signaling pathway.

Tian, Jia-Nan

Astemizole protects against human umbilical vein endothelial cell injury induced by hydrogen peroxide via the p53 signaling pathway. [electronic resource] - Molecular medicine reports Jun 2017 - 4286-4290 p. digital

Publication Type: Journal Article

1791-3004

10.3892/mmr.2017.6497 doi


Antioxidants--metabolism
Apoptosis--drug effects
Astemizole--pharmacology
Cell Survival--drug effects
Cells, Cultured
Glutathione Peroxidase--metabolism
Human Umbilical Vein Endothelial Cells--drug effects
Humans
Hydrogen Peroxide--pharmacology
Malondialdehyde--metabolism
Nitric Oxide--metabolism
Oxidative Stress--drug effects
Protective Agents--pharmacology
Reactive Oxygen Species--metabolism
Signal Transduction--drug effects
Superoxide Dismutase--metabolism
Tumor Suppressor Protein p53--metabolism