Phase I trial of systemic administration of Edmonston strain of measles virus genetically engineered to express the sodium iodide symporter in patients with recurrent or refractory multiple myeloma.
Dispenzieri, A
Phase I trial of systemic administration of Edmonston strain of measles virus genetically engineered to express the sodium iodide symporter in patients with recurrent or refractory multiple myeloma. [electronic resource] - Leukemia 12 2017 - 2791-2798 p. digital
Publication Type: Clinical Trial, Phase I; Journal Article
1476-5551
10.1038/leu.2017.120 doi
Adult
Aged
Aged, 80 and over
Animals
Cell Line, Tumor
Disease Models, Animal
Drug Resistance, Neoplasm
Female
Genetic Engineering
Genetic Therapy--adverse effects
Genetic Vectors--administration & dosage
Humans
Male
Measles virus--genetics
Mice
Middle Aged
Multiple Myeloma--diagnosis
Oncolytic Virotherapy--adverse effects
Oncolytic Viruses--genetics
Recurrence
Single Photon Emission Computed Tomography Computed Tomography
Symporters--genetics
Tissue Distribution
Treatment Outcome
Xenograft Model Antitumor Assays
Phase I trial of systemic administration of Edmonston strain of measles virus genetically engineered to express the sodium iodide symporter in patients with recurrent or refractory multiple myeloma. [electronic resource] - Leukemia 12 2017 - 2791-2798 p. digital
Publication Type: Clinical Trial, Phase I; Journal Article
1476-5551
10.1038/leu.2017.120 doi
Adult
Aged
Aged, 80 and over
Animals
Cell Line, Tumor
Disease Models, Animal
Drug Resistance, Neoplasm
Female
Genetic Engineering
Genetic Therapy--adverse effects
Genetic Vectors--administration & dosage
Humans
Male
Measles virus--genetics
Mice
Middle Aged
Multiple Myeloma--diagnosis
Oncolytic Virotherapy--adverse effects
Oncolytic Viruses--genetics
Recurrence
Single Photon Emission Computed Tomography Computed Tomography
Symporters--genetics
Tissue Distribution
Treatment Outcome
Xenograft Model Antitumor Assays