JMJD3 suppresses stem cell-like characteristics in breast cancer cells by downregulation of Oct4 independently of its demethylase activity.

Xun, Jing

JMJD3 suppresses stem cell-like characteristics in breast cancer cells by downregulation of Oct4 independently of its demethylase activity. [electronic resource] - Oncotarget Mar 2017 - 21918-21929 p. digital

Publication Type: Journal Article

1949-2553

10.18632/oncotarget.15747 doi


Animals
Apoptosis
Biomarkers, Tumor--genetics
Bone Density Conservation Agents--pharmacology
Breast Neoplasms--drug therapy
Cell Proliferation
DNA Methylation--drug effects
Ergocalciferols--pharmacology
Female
Gene Expression Regulation, Neoplastic
Histone Demethylases--metabolism
Humans
Jumonji Domain-Containing Histone Demethylases--genetics
Mice
Mice, Inbred BALB C
Mice, Nude
Neoplastic Stem Cells--drug effects
Octamer Transcription Factor-3--antagonists & inhibitors
Tumor Cells, Cultured
Xenograft Model Antitumor Assays