Pharmacological inhibition of Src kinase protects against acute kidney injury in a murine model of renal ischemia/reperfusion.
Xiong, Chongxiang
Pharmacological inhibition of Src kinase protects against acute kidney injury in a murine model of renal ischemia/reperfusion. [electronic resource] - Oncotarget May 2017 - 31238-31253 p. digital
Publication Type: Journal Article
1949-2553
10.18632/oncotarget.16114 doi
Acute Kidney Injury--drug therapy
Adherens Junctions--metabolism
Animals
Apoptosis--drug effects
Disease Models, Animal
Enzyme Activation--drug effects
Epithelial Cells--drug effects
Kidney Function Tests
Kidney Tubules--drug effects
Macrophages--metabolism
Mice
Mitogen-Activated Protein Kinase 1--metabolism
Mitogen-Activated Protein Kinase 3--metabolism
NF-kappa B--metabolism
Protective Agents--pharmacology
Protein Kinase Inhibitors--pharmacology
Pyrazoles--pharmacology
Pyrimidines--pharmacology
Reperfusion Injury--drug therapy
STAT3 Transcription Factor--metabolism
Tight Junction Proteins--metabolism
src-Family Kinases--antagonists & inhibitors
Pharmacological inhibition of Src kinase protects against acute kidney injury in a murine model of renal ischemia/reperfusion. [electronic resource] - Oncotarget May 2017 - 31238-31253 p. digital
Publication Type: Journal Article
1949-2553
10.18632/oncotarget.16114 doi
Acute Kidney Injury--drug therapy
Adherens Junctions--metabolism
Animals
Apoptosis--drug effects
Disease Models, Animal
Enzyme Activation--drug effects
Epithelial Cells--drug effects
Kidney Function Tests
Kidney Tubules--drug effects
Macrophages--metabolism
Mice
Mitogen-Activated Protein Kinase 1--metabolism
Mitogen-Activated Protein Kinase 3--metabolism
NF-kappa B--metabolism
Protective Agents--pharmacology
Protein Kinase Inhibitors--pharmacology
Pyrazoles--pharmacology
Pyrimidines--pharmacology
Reperfusion Injury--drug therapy
STAT3 Transcription Factor--metabolism
Tight Junction Proteins--metabolism
src-Family Kinases--antagonists & inhibitors