Curcumin exhibits anti-tumor effect and attenuates cellular migration via Slit-2 mediated down-regulation of SDF-1 and CXCR4 in endometrial adenocarcinoma cells.

Sirohi, Vijay Kumar

Curcumin exhibits anti-tumor effect and attenuates cellular migration via Slit-2 mediated down-regulation of SDF-1 and CXCR4 in endometrial adenocarcinoma cells. [electronic resource] - The Journal of nutritional biochemistry 06 2017 - 60-70 p. digital

Publication Type: Journal Article

1873-4847

10.1016/j.jnutbio.2016.12.021 doi


Animals
Apoptosis--drug effects
Cell Line, Tumor
Cell Movement--drug effects
Cell Survival--drug effects
Chemokine CXCL12--genetics
Chlorocebus aethiops
Curcumin--pharmacology
Down-Regulation
Endometrial Neoplasms--drug therapy
Female
Gene Expression Regulation, Neoplastic
Humans
Intercellular Signaling Peptides and Proteins--genetics
Matrix Metalloproteinase 2--genetics
Matrix Metalloproteinase 9--genetics
Mice
Mice, Inbred NOD
Mice, SCID
Nerve Tissue Proteins--genetics
Reactive Oxygen Species--metabolism
Receptors, CXCR4--genetics
Signal Transduction
Vero Cells
Xenograft Model Antitumor Assays
Slit Homolog 2 Protein