SPDEF Induces Quiescence of Colorectal Cancer Cells by Changing the Transcriptional Targets of β-catenin.

Lo, Yuan-Hung

SPDEF Induces Quiescence of Colorectal Cancer Cells by Changing the Transcriptional Targets of β-catenin. [electronic resource] - Gastroenterology 07 2017 - 205-218.e8 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1528-0012

10.1053/j.gastro.2017.03.048 doi


Adenoma--chemistry
Animals
Axin Protein--genetics
Carcinogenesis
Cell Cycle--genetics
Cell Proliferation
Chromatin--metabolism
Colon
Colorectal Neoplasms--chemistry
Cyclin D1--genetics
Gene Expression Regulation, Neoplastic
HCT116 Cells
HEK293 Cells
Humans
Hyaluronan Receptors--analysis
Intestinal Mucosa--chemistry
Lymphoid Enhancer-Binding Factor 1--metabolism
Male
Mice
Organoids
Promoter Regions, Genetic
Proto-Oncogene Proteins c-ets--genetics
Proto-Oncogene Proteins c-myc--genetics
Receptor, EphB2--genetics
Stem Cells
TCF Transcription Factors--metabolism
Transcription, Genetic--genetics
Transfection
Wnt Signaling Pathway
beta Catenin--genetics