Inhibition of monocarboxyate transporter 1 by AZD3965 as a novel therapeutic approach for diffuse large B-cell lymphoma and Burkitt lymphoma.

Noble, Richard A

Inhibition of monocarboxyate transporter 1 by AZD3965 as a novel therapeutic approach for diffuse large B-cell lymphoma and Burkitt lymphoma. [electronic resource] - Haematologica 07 2017 - 1247-1257 p. digital

Publication Type: Journal Article

1592-8721

10.3324/haematol.2016.163030 doi


Antineoplastic Agents--pharmacology
Biomarkers
Burkitt Lymphoma--drug therapy
Cell Death--drug effects
Cell Line, Tumor
Drug Resistance, Neoplasm
Electron Transport Complex I--antagonists & inhibitors
Energy Metabolism--drug effects
Humans
Lactic Acid--metabolism
Lymphoma, Large B-Cell, Diffuse--drug therapy
Mitochondria--drug effects
Monocarboxylic Acid Transporters--antagonists & inhibitors
Muscle Proteins--genetics
Oxidative Phosphorylation--drug effects
Pyrimidinones--pharmacology
Symporters--antagonists & inhibitors
Thiophenes--pharmacology