Estimating the selective effects of heterozygous protein-truncating variants from human exome data.

Cassa, Christopher A

Estimating the selective effects of heterozygous protein-truncating variants from human exome data. [electronic resource] - Nature genetics May 2017 - 806-810 p. digital

Publication Type: Journal Article

1546-1718

10.1038/ng.3831 doi


Algorithms
Animals
Bayes Theorem
Exome--genetics
Gene Frequency
Genetic Predisposition to Disease--genetics
Genetic Variation
Genome-Wide Association Study--methods
Genotype
Heterozygote
Humans
Mice, Knockout
Models, Genetic
Mutation
Selection, Genetic
Sequence Analysis, DNA--methods