Lithocholic Acid Hydroxyamide Destabilizes Cyclin D1 and Induces G

Magiera, Katarzyna

Lithocholic Acid Hydroxyamide Destabilizes Cyclin D1 and Induces G [electronic resource] - Cell chemical biology Apr 2017 - 458-470.e18 p. digital

Publication Type: Journal Article

2451-9448

10.1016/j.chembiol.2017.03.002 doi


Catalytic Domain
Cell Line, Tumor
Cell Proliferation--drug effects
Cell Survival--drug effects
Cyclin D1--antagonists & inhibitors
Cyclin-Dependent Kinase Inhibitor p21--metabolism
Cyclin-Dependent Kinase Inhibitor p27--metabolism
Cycloheximide--chemistry
Down-Regulation--drug effects
Endopeptidases--chemistry
G1 Phase Cell Cycle Checkpoints--drug effects
Glycogen Synthase Kinase 3 beta--metabolism
HCT116 Cells
Humans
Lithocholic Acid--analogs & derivatives
MCF-7 Cells
Proto-Oncogene Proteins c-akt--metabolism
RNA Interference
Signal Transduction--drug effects
Tumor Suppressor Protein p53--deficiency
Ubiquitin Thiolesterase