Neuroprotective and axonal outgrowth-promoting effects of tetramethylpyrazine nitrone in chronic cerebral hypoperfusion rats and primary hippocampal neurons exposed to hypoxia.

Zhang, Tao

Neuroprotective and axonal outgrowth-promoting effects of tetramethylpyrazine nitrone in chronic cerebral hypoperfusion rats and primary hippocampal neurons exposed to hypoxia. [electronic resource] - Neuropharmacology 05 2017 - 137-147 p. digital

Publication Type: Journal Article

1873-7064

10.1016/j.neuropharm.2017.03.022 doi


Animals
Axons--drug effects
Caspase 3--metabolism
Cell Hypoxia--drug effects
Cells, Cultured
Cerebrovascular Circulation--drug effects
Disease Models, Animal
Embryo, Mammalian
Glucose--deficiency
Hippocampus--cytology
Hypoxia-Ischemia, Brain--drug therapy
Male
Maze Learning--drug effects
Nerve Tissue Proteins--metabolism
Neurons--drug effects
Neuroprotective Agents--therapeutic use
Pyrazines--therapeutic use
Rats
Rats, Sprague-Dawley
Recognition, Psychology--drug effects