Isocitrate dehydrogenase mutations suppress STAT1 and CD8+ T cell accumulation in gliomas.

Kohanbash, Gary

Isocitrate dehydrogenase mutations suppress STAT1 and CD8+ T cell accumulation in gliomas. [electronic resource] - The Journal of clinical investigation Apr 2017 - 1425-1437 p. digital

Publication Type: Journal Article

1558-8238

10.1172/JCI90644 doi


Animals
Brain Neoplasms--enzymology
CD8-Positive T-Lymphocytes--enzymology
Cancer Vaccines--immunology
Cell Line, Tumor
Chemokines--metabolism
Chemotaxis
Glioma--enzymology
Humans
Isocitrate Dehydrogenase--genetics
Lymphocytes, Tumor-Infiltrating--enzymology
Mice, Inbred C57BL
Neoplasm Transplantation
STAT1 Transcription Factor--metabolism
T-Lymphocytes, Cytotoxic--enzymology
Vaccination