Nitroxoline shows antimyeloma activity by targeting the TRIM25/p53 axle.

Mao, Hongwu

Nitroxoline shows antimyeloma activity by targeting the TRIM25/p53 axle. [electronic resource] - Anti-cancer drugs 04 2017 - 376-383 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1473-5741

10.1097/CAD.0000000000000466 doi


A549 Cells
Animals
Cell Line, Tumor
Drug Screening Assays, Antitumor
Female
Humans
Mice
Mice, Nude
Molecular Targeted Therapy
Multiple Myeloma--drug therapy
Nitroquinolines--pharmacology
Off-Label Use
Random Allocation
Transcription Factors--biosynthesis
Tripartite Motif Proteins--biosynthesis
Tumor Suppressor Protein p53--metabolism
Ubiquitin-Protein Ligases--biosynthesis
Xenograft Model Antitumor Assays