Correlation between clinical response to sorafenib in hepatocellular carcinoma treatment and polymorphisms of P-glycoprotein (ABCB1) and of breast cancer resistance protein (ABCG2): monocentric study.

Tandia, Mahamadou

Correlation between clinical response to sorafenib in hepatocellular carcinoma treatment and polymorphisms of P-glycoprotein (ABCB1) and of breast cancer resistance protein (ABCG2): monocentric study. [electronic resource] - Cancer chemotherapy and pharmacology 04 2017 - 759-766 p. digital

Publication Type: Journal Article

1432-0843

10.1007/s00280-017-3268-y doi


ATP Binding Cassette Transporter, Subfamily B--genetics
ATP Binding Cassette Transporter, Subfamily G, Member 2--genetics
Adult
Aged
Aged, 80 and over
Antineoplastic Agents--pharmacokinetics
Breast Neoplasms--drug therapy
Carcinoma, Hepatocellular--drug therapy
DNA--genetics
Drug Monitoring
Female
Genotype
Humans
Liver Neoplasms--drug therapy
Male
Middle Aged
Neoplasm Proteins--genetics
Niacinamide--analogs & derivatives
Phenylurea Compounds--pharmacokinetics
Polymorphism, Genetic--genetics
Polymorphism, Single Nucleotide--genetics
Protein Kinase Inhibitors--pharmacokinetics
Sorafenib
Treatment Outcome