Salvianolic acid B inhibits IL-1β-induced inflammatory cytokine production in human osteoarthritis chondrocytes and has a protective effect in a mouse osteoarthritis model.
Lou, Yiting
Salvianolic acid B inhibits IL-1β-induced inflammatory cytokine production in human osteoarthritis chondrocytes and has a protective effect in a mouse osteoarthritis model. [electronic resource] - International immunopharmacology May 2017 - 31-37 p. digital
Publication Type: Journal Article
1878-1705
10.1016/j.intimp.2017.02.021 doi
Animals
Anti-Inflammatory Agents--therapeutic use
Benzofurans--therapeutic use
Cartilage--pathology
Chondrocytes--drug effects
Cytokines--metabolism
Disease Models, Animal
Humans
Inflammation--drug therapy
Interleukin-1beta--immunology
Male
Matrix Metalloproteinase 13
Menisci, Tibial--surgery
Mice
Mice, Inbred C57BL
NF-kappa B--metabolism
Nitric Oxide--metabolism
Osteoarthritis--drug therapy
Phosphorylation--drug effects
Signal Transduction--drug effects
Salvianolic acid B inhibits IL-1β-induced inflammatory cytokine production in human osteoarthritis chondrocytes and has a protective effect in a mouse osteoarthritis model. [electronic resource] - International immunopharmacology May 2017 - 31-37 p. digital
Publication Type: Journal Article
1878-1705
10.1016/j.intimp.2017.02.021 doi
Animals
Anti-Inflammatory Agents--therapeutic use
Benzofurans--therapeutic use
Cartilage--pathology
Chondrocytes--drug effects
Cytokines--metabolism
Disease Models, Animal
Humans
Inflammation--drug therapy
Interleukin-1beta--immunology
Male
Matrix Metalloproteinase 13
Menisci, Tibial--surgery
Mice
Mice, Inbred C57BL
NF-kappa B--metabolism
Nitric Oxide--metabolism
Osteoarthritis--drug therapy
Phosphorylation--drug effects
Signal Transduction--drug effects