Chrysin induces death of prostate cancer cells by inducing ROS and ER stress.

Ryu, Soomin

Chrysin induces death of prostate cancer cells by inducing ROS and ER stress. [electronic resource] - Journal of cellular physiology Dec 2017 - 3786-3797 p. digital

Publication Type: Journal Article

1097-4652

10.1002/jcp.25861 doi


Antineoplastic Agents, Phytogenic--pharmacology
Apoptosis--drug effects
Cell Line, Tumor
Cell Proliferation--drug effects
Dose-Response Relationship, Drug
Endoplasmic Reticulum Chaperone BiP
Endoplasmic Reticulum Stress--drug effects
Eukaryotic Initiation Factor-2--metabolism
Flavonoids--pharmacology
G1 Phase Cell Cycle Checkpoints--drug effects
Heat-Shock Proteins--metabolism
Humans
Lipid Peroxidation--drug effects
Male
Membrane Potential, Mitochondrial--drug effects
Mitogen-Activated Protein Kinases--metabolism
Oxidative Stress--drug effects
Phosphatidylinositol 3-Kinase--metabolism
Proliferating Cell Nuclear Antigen--metabolism
Prostatic Neoplasms--drug therapy
Proto-Oncogene Proteins c-akt--metabolism
Reactive Oxygen Species--metabolism
Ribosomal Protein S6 Kinases--metabolism
Signal Transduction--drug effects
Unfolded Protein Response--drug effects
eIF-2 Kinase--metabolism