Rare genetic variant in the CFB gene presenting as atypical hemolytic uremic syndrome and immune complex diffuse membranoproliferative glomerulonephritis, with crescents, successfully treated with eculizumab.

Alfakeeh, Khalid

Rare genetic variant in the CFB gene presenting as atypical hemolytic uremic syndrome and immune complex diffuse membranoproliferative glomerulonephritis, with crescents, successfully treated with eculizumab. [electronic resource] - Pediatric nephrology (Berlin, Germany) 05 2017 - 885-891 p. digital

Publication Type: Journal Article

1432-198X

10.1007/s00467-016-3577-0 doi


Antibodies, Monoclonal, Humanized--therapeutic use
Child
Complement C3--analysis
Complement Factor B--genetics
Creatinine--blood
DNA Mutational Analysis
Exons--genetics
Glomerulonephritis, Membranoproliferative--drug therapy
Hemolytic-Uremic Syndrome--drug therapy
Humans
Kidney Failure, Chronic--prevention & control
Kidney Function Tests
Male
Mutation