Dimerisation induced formation of the active site and the identification of three metal sites in EAL-phosphodiesterases.

Bellini, Dom

Dimerisation induced formation of the active site and the identification of three metal sites in EAL-phosphodiesterases. [electronic resource] - Scientific reports 02 2017 - 42166 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

2045-2322

10.1038/srep42166 doi


Bacterial Proteins--chemistry
Biocatalysis
Catalytic Domain
Cations, Divalent
Cloning, Molecular
Crystallography, X-Ray
Cyclic GMP--analogs & derivatives
Escherichia coli--genetics
Gene Expression
Genetic Vectors--chemistry
Hydrolysis
Kinetics
Magnesium--chemistry
Manganese--chemistry
Models, Molecular
Phosphoric Diester Hydrolases--chemistry
Protein Binding
Protein Conformation, alpha-Helical
Protein Conformation, beta-Strand
Protein Interaction Domains and Motifs
Protein Multimerization
Pseudomonas aeruginosa--chemistry
Recombinant Proteins--chemistry
Substrate Specificity