Selumetinib Inhibits Melanoma Metastasis to Mouse Liver

Ryu, Seung-Hee

Selumetinib Inhibits Melanoma Metastasis to Mouse Liver [electronic resource] - Anticancer research 02 2017 - 607-614 p. digital

Publication Type: Journal Article

1791-7530

10.21873/anticanres.11354 doi


Administration, Oral
Animals
Apoptosis--drug effects
Benzimidazoles--administration & dosage
Cell Line, Tumor
Cell Proliferation--drug effects
Epithelial-Mesenchymal Transition--drug effects
G1 Phase Cell Cycle Checkpoints--drug effects
Gene Expression Regulation, Neoplastic--drug effects
Humans
Immunoblotting
Integrin alpha5--genetics
Jagged-1 Protein--genetics
Liver Neoplasms--genetics
Male
Melanoma--drug therapy
Mice, Inbred BALB C
Mice, Nude
Reverse Transcriptase Polymerase Chain Reaction
Transforming Growth Factor beta1--genetics
Xenograft Model Antitumor Assays