Genotoxicity and effects on rat liver drug-metabolizing enzymes by possible substitutes for 4,4'-methylene bis(2-chloroaniline).

Wu, K

Genotoxicity and effects on rat liver drug-metabolizing enzymes by possible substitutes for 4,4'-methylene bis(2-chloroaniline). [electronic resource] - Carcinogenesis Nov 1989 - 2119-22 p. digital

Publication Type: Journal Article

0143-3334

10.1093/carcin/10.11.2119 doi


4-Aminobenzoic Acid--pharmacology
Aniline Compounds--pharmacology
Animals
Benzhydryl Compounds--pharmacology
Biotransformation--drug effects
Cytochrome P-450 CYP1A1
Cytochrome P-450 Enzyme System--metabolism
In Vitro Techniques
Methylenebis(chloroaniline)--pharmacology
Microsomes, Liver--enzymology
Mixed Function Oxygenases--metabolism
Mutagenicity Tests
Mutagens
Oxidoreductases--metabolism
Phenylenediamines--pharmacology
Propylene Glycols--pharmacology
Rats
Rats, Inbred Strains
Salmonella typhimurium--drug effects
Structure-Activity Relationship
para-Aminobenzoates