Design and synthesis of a novel series of 4-heteroarylamino-1'-azaspiro[oxazole-5,3'-bicyclo[2.2.2]octanes as α7 nicotinic receptor agonists 2. Development of 4-heteroaryl SAR.

Iwuagwu, Christiana

Design and synthesis of a novel series of 4-heteroarylamino-1'-azaspiro[oxazole-5,3'-bicyclo[2.2.2]octanes as α7 nicotinic receptor agonists 2. Development of 4-heteroaryl SAR. [electronic resource] - Bioorganic & medicinal chemistry letters 03 2017 - 1261-1266 p. digital

Publication Type: Journal Article

1464-3405

10.1016/j.bmcl.2017.01.058 doi


Animals
Cognition--drug effects
Cognition Disorders--drug therapy
Disease Models, Animal
Drug Design
Mice
Molecular Structure
Octanes--chemical synthesis
Pyrimidines--chemical synthesis
Spiro Compounds--chemical synthesis
Structure-Activity Relationship
alpha7 Nicotinic Acetylcholine Receptor--agonists