Loss of Ssq1 leads to mitochondrial dysfunction, activation of autophagy and cell cycle arrest due to iron overload triggered by mitochondrial iron-sulfur cluster assembly defects in Candida albicans.

Dong, Yijie

Loss of Ssq1 leads to mitochondrial dysfunction, activation of autophagy and cell cycle arrest due to iron overload triggered by mitochondrial iron-sulfur cluster assembly defects in Candida albicans. [electronic resource] - The international journal of biochemistry & cell biology 04 2017 - 44-55 p. digital

Publication Type: Journal Article

1878-5875

10.1016/j.biocel.2017.01.021 doi


Autophagy--genetics
Candida albicans--cytology
Cell Cycle Checkpoints--genetics
Cell Survival--genetics
HSP70 Heat-Shock Proteins--genetics
Iron--metabolism
Iron-Sulfur Proteins--genetics
Loss of Function Mutation
Mitochondria--genetics
Mitochondrial Proteins--genetics
Models, Biological
Real-Time Polymerase Chain Reaction
Saccharomyces cerevisiae Proteins--genetics
Sequence Deletion
Virulence--genetics