FM807, a curcumin analogue, shows potent antitumor effects in nasopharyngeal carcinoma cells by heat shock protein 90 inhibition.

Ye, Min

FM807, a curcumin analogue, shows potent antitumor effects in nasopharyngeal carcinoma cells by heat shock protein 90 inhibition. [electronic resource] - Oncotarget Feb 2017 - 15364-15376 p. digital

Publication Type: Journal Article

1949-2553

10.18632/oncotarget.14970 doi


Animals
Antineoplastic Agents--pharmacology
Apoptosis--drug effects
Blotting, Western
Cell Line, Tumor
Cell Proliferation--drug effects
Curcumin--analogs & derivatives
Cyclin D1--metabolism
ErbB Receptors--genetics
G1 Phase Cell Cycle Checkpoints--drug effects
HSP90 Heat-Shock Proteins--antagonists & inhibitors
Humans
MAP Kinase Signaling System--drug effects
Male
Mice, Inbred BALB C
Mice, Nude
Nasopharyngeal Neoplasms--drug therapy
Protein Binding--drug effects
RNA Interference
Reverse Transcriptase Polymerase Chain Reaction
Xenograft Model Antitumor Assays
beta Catenin--metabolism