Human Carboxylesterase 2 Reverses Obesity-Induced Diacylglycerol Accumulation and Glucose Intolerance.

Ruby, Maxwell A

Human Carboxylesterase 2 Reverses Obesity-Induced Diacylglycerol Accumulation and Glucose Intolerance. [electronic resource] - Cell reports 01 2017 - 636-646 p. digital

Publication Type: Journal Article

2211-1247

10.1016/j.celrep.2016.12.070 doi


Animals
Carboxylesterase--antagonists & inhibitors
Carboxylic Ester Hydrolases--antagonists & inhibitors
Cells, Cultured
Diet, High-Fat
Diglycerides--metabolism
Endoplasmic Reticulum Stress
Genetic Vectors--genetics
Glucose--metabolism
Glucose Intolerance--metabolism
Hepatocytes--cytology
Humans
Insulin--metabolism
Insulin Receptor Substrate Proteins--genetics
Insulin Resistance
Lipid Peroxidation
Male
Mice
Mice, Inbred C57BL
Obesity--metabolism
TOR Serine-Threonine Kinases--genetics