Evaluating the therapeutic potential of idebenone and related quinone analogues in Leber hereditary optic neuropathy.
Yu-Wai-Man, Patrick
Evaluating the therapeutic potential of idebenone and related quinone analogues in Leber hereditary optic neuropathy. [electronic resource] - Mitochondrion 09 2017 - 36-42 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1872-8278
10.1016/j.mito.2017.01.004 doi
Adenosine Triphosphate--biosynthesis
Adolescent
Antioxidants--metabolism
Cells, Cultured
Energy Metabolism--drug effects
Fibroblasts--drug effects
Humans
Male
Middle Aged
Optic Atrophy, Hereditary, Leber--pathology
Quinones--metabolism
Reactive Oxygen Species--analysis
Ubiquinone--analogs & derivatives
Young Adult
Evaluating the therapeutic potential of idebenone and related quinone analogues in Leber hereditary optic neuropathy. [electronic resource] - Mitochondrion 09 2017 - 36-42 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1872-8278
10.1016/j.mito.2017.01.004 doi
Adenosine Triphosphate--biosynthesis
Adolescent
Antioxidants--metabolism
Cells, Cultured
Energy Metabolism--drug effects
Fibroblasts--drug effects
Humans
Male
Middle Aged
Optic Atrophy, Hereditary, Leber--pathology
Quinones--metabolism
Reactive Oxygen Species--analysis
Ubiquinone--analogs & derivatives
Young Adult