Disease-associated mutations identify a novel region in human STING necessary for the control of type I interferon signaling.

Melki, Isabelle

Disease-associated mutations identify a novel region in human STING necessary for the control of type I interferon signaling. [electronic resource] - The Journal of allergy and clinical immunology 08 2017 - 543-552.e5 p. digital

Publication Type: Case Reports; Journal Article

1097-6825

10.1016/j.jaci.2016.10.031 doi


Adolescent
Adult
Amino Acid Substitution
Child
Female
HEK293 Cells
Humans
Inflammation--genetics
Interferon Type I--genetics
Male
Membrane Proteins--genetics
Mutation
STAT1 Transcription Factor--metabolism
Signal Transduction