Choline Kinase α Mediates Interactions Between the Epidermal Growth Factor Receptor and Mechanistic Target of Rapamycin Complex 2 in Hepatocellular Carcinoma Cells to Promote Drug Resistance and Xenograft Tumor Progression.

Lin, Xi-Meng

Choline Kinase α Mediates Interactions Between the Epidermal Growth Factor Receptor and Mechanistic Target of Rapamycin Complex 2 in Hepatocellular Carcinoma Cells to Promote Drug Resistance and Xenograft Tumor Progression. [electronic resource] - Gastroenterology 04 2017 - 1187-1202 p. digital

Publication Type: Journal Article

1528-0012

10.1053/j.gastro.2016.12.033 doi


Animals
Antineoplastic Agents--pharmacology
Carcinoma, Hepatocellular--drug therapy
Cell Line
Cell Line, Tumor
Cell Movement--genetics
Choline Kinase--genetics
Drug Resistance, Neoplasm--genetics
ErbB Receptors--antagonists & inhibitors
Erlotinib Hydrochloride--pharmacology
Gefitinib
Hep G2 Cells
Humans
Immunoblotting
Immunohistochemistry
Liver Neoplasms--drug therapy
Mechanistic Target of Rapamycin Complex 2
Mice
Multiprotein Complexes--metabolism
Neoplasm Invasiveness--genetics
Neoplasm Transplantation
Quinazolines--pharmacology
RNA, Messenger--metabolism
TOR Serine-Threonine Kinases--metabolism
Wound Healing--genetics
Xenograft Model Antitumor Assays