SOX2 promotes lineage plasticity and antiandrogen resistance in TP53- and RB1-deficient prostate cancer.

Mu, Ping

SOX2 promotes lineage plasticity and antiandrogen resistance in TP53- and RB1-deficient prostate cancer. [electronic resource] - Science (New York, N.Y.) 01 2017 - 84-88 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

1095-9203

10.1126/science.aah4307 doi


Androgen Antagonists--therapeutic use
Benzamides
Cell Line, Tumor
Cell Lineage
Cell Plasticity
Humans
Male
Nitriles
Phenylthiohydantoin--analogs & derivatives
Prostatic Neoplasms--drug therapy
Retinoblastoma Binding Proteins--genetics
SOXB1 Transcription Factors--genetics
Tumor Suppressor Protein p53--genetics
Ubiquitin-Protein Ligases--genetics